Small study results are not promising. Malaria Drug Chloroquine No Better Than Regular Coronavirus Care, Study Finds You may have also seen suggestions that hydroxychloroquine (Plaquenil) be combined with azithromycin (Z Pack) for Covid-19. I'm skeptical. Plaquenil is an antimalarial drug often used for people with autoimmune diseases like Lupus and Rheumatoid Arthritis. I took it for a couple of years early in my battle with RA. It is used because it suppresses the immune system, and that seems contrarian for use against Covid-19. Azithromycin is an antibiotic and seems unlikely to be of help against this virus as well. Is there something I'm missing here?